Ehh I’ll disagree. the only medication they actually show to decrease mortality is steroid however if given too early in the course before inflammatory response are high then you run the risk of immunosuppressive on and getting concurrent bacterial infection. Remdesivir only show to decrease symptoms quicker but no improvement in mortality. Toccizulomab is the same. Only in setting of cytokines storm. Given earlier you get chance of massive bacterial infection
Remdesivir is a joke, attested by many doctors, they use it because they are told to, but the results with Remdesivir aren't very good at all, not to mention giving it in a hospital setting at that point it's even more useless. Remdesivir has one mechanism of action to cut the virus but it should be used early, but either way, it's not very good.
Steroids are to be given day 7-8 because of what you said, that much is known.
But really my post is on Ivermectin. The same group (the FLCCC) that was screaming at the government to endorse corticosteroids last April because it was working and saving lives (the government in July finally agreed to endorse it) were screaming at the government in December to deploy Ivermectin immediately to again save lives.
Ivermectin has been used for 40 years as an antiparasitic, it is extremely safe (16 deaths, 4,700 adverse events since 1992 --- compare that to remdesivir that's been out basically less than a year), is in the WHO'S most essential medicines list, and won the Nobel prize in 2015 for eradicating river blindness in Africa.
There's several meta-analyses on Ivermectin from very well respected groups, 26 randomized control trials, many observation trials- 50 trials overall, 15,000 patients around the world, 80-90% decrease in mortality when taken early, and close to 90% decrease of mortality when taken prophylactically.
It's mechanism of action is very well explained by some docs, it interferes with the virus attaching to the ACE-2 receptor among other things and also tames inflammation. It works plain and simple, and again, is best when used early.
The problem is it's cheap and off-patent, sadly.
And Ivermectin isn't the only medication that works, there's fluvoxamine, Budesonide just had a study come out showing that it cut mortality by 92%, and others. The data on Ivermectin is pretty overwhelming though