A multitude of reactions can occur during a psychedelic crisis. Some users can experience many general senses of fear. Some users may be catapulted into an anxiety attack, a disabling reaction in which one is overcome with extreme fright. A user may be overwhelmed with the disconnection many psychedelics cause, and fear that they are going insane or will never return to reality. This can cause the user to fall into a profound depression. Other reactions include an amplification of nameless fears; that is, fears that are unfounded and are usually not encountered in normality.
Users may exhibit actions suggesting harm to themselves or others around them. This harm could take the form of suicidal ideation, or full blown suicide attempts. Because of the magnification of emotions many psychedelics cause, death or thoughts of death can cause intensely adverse reactions in some users. Users can believe that their death is imminent or that the very universe itself is collapsing. Rapidly accelerated aging of other people may be experienced, irritating the aforementioned fears even more.
Some users may experience disorientation. The normal views of time, space, and person can be substantially altered, causing fear. Some can worsen their condition by trying to fight the
psychedelic experience after embarkment. There can be illusions of insects crawling over or into one's self, or of being in dirty places such as sewers.