If you have any interest (and if it is still there, you didn't say when you would be there), check out the King Tut exhibit:
http://www.tutsanfrancisco.org/
There are all the "traditional SF" things as well: Alcatraz, Fisherman's Wharf, Coit Tower, Golden Gate Bridge, Fort Point, Lombard Street east of Hyde (1 block of
very curvy road), Chinatown (very cool to walk through, if interested), The Stinking Rose Restaraunt (only if you like garlic), the Presidio, Golden Gate Park (and everything within that is to see there), and probably 100 things I am forgetting.
Are you staying in SF or venturing outside the city as well? How long are you "here"?