I know it is not exactly the same, but it sounds a lot like Another Life on Netflix. Have you watched that? How does it compare? Sounds like it may be more of a "wife friendly" version (at least in my house!) of Another Life. (Wife leaves her family to head up a space voyage, some family drama mixed in, troubles with the ship during the trip, personality clashes on board, etc., etc.)
Although it seems like Away may be more like the Apollo 13, Gravity, or The Martian movies and Another Life is more your typical sci-fi action/horror movie mashup (and not always in the best way).