I'm not so sure. This Philly team is pretty lacking in talent, and very young. The average age of this team (not counting the out-for-the-season JRich or Embiid) is 23.1 years old. They've only got three guys playing that were even drafted in the first round (MCW, Noel, and Wroten) and two of those guys are coming off of injury. They have an incredible nine (9!!) undrafted players that have gotten minutes this year. These guys are incredibly raw - of these nine undrafted guys only one has more than two years in the league (not counting this year), and that's Malcolm Thomas, who hadn't gotten up to 150 NBA minutes before he stepped on the court for the Sixers this year. These undrafted, untested guys have accounted for FIFTY-THREE PERCENT of the Sixers' minutes thus far this year.
On the other hand, Kentucky is running a ten-man rotation with at least 8 guys that are shoe-ins to be drafted: An. Harrison, Aa. Harrison, Lyles, Poythress, Cauley-Stein, Towns, D. Johnson, M. Lee. Most of these guys are borderline first-rounders at worst, and Cauley-Stein and Poythress are juniors while only Towns (in contention for #1 overall) and Lyles are freshmen. And the team looks fantastic. They're playing great D and they've got offensive threats all over the court.
Kentucky against a real NBA team? Sure, they get crushed. But these Sixers are a completely different element altogether. Their margin of victory is currently -16.36, which is the single worst MOV in NBA history. Only 17 teams have ever broken the -10 MOV barrier (including last year's 76ers), and only three other teams have broken -12. They are on track to be the single worst NBA team in the history of the NBA.
I would bet on Kentucky. Seriously.